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What does rubella primarily affect in the body?

  1. Respiratory system

  2. Cardiovascular system

  3. Immune system

  4. Endocrine system

The correct answer is: Respiratory system

Rubella primarily affects the respiratory system, particularly through the initial entry of the virus. The infection starts in the upper respiratory tract, and the virus can spread throughout the body via the bloodstream. Although it can have systemic effects, particularly among pregnant women where it poses a risk to fetal development, the primary impact of the virus occurs within the respiratory tract. This includes symptoms like a mild rash and fever, which are initiated after the virus replicates in the respiratory mucosa. Thus, the correct understanding of rubella's primary site of action underlines its respiratory nature, distinguishing it from other systems that may not be the first affected by the virus.